Years since biopsy | |||||
---|---|---|---|---|---|
1 y | 5 y | 10 y | 20 y | 30 y | |
Compared with matched references a | |||||
HR (95%CIs) | 1.21 (1.18, 1.25) | 1.01 (1.00, 1.03) | 1.00 (0.98, 1.02) | 1.05 (1.03, 1.07) | 1.08 (1.05, 1.12) |
Cumulative incidence (95% CIs), % | |||||
Reference | 0.32 (0.31, 0.33) | 3.00 (2.98, 3.03) | 6.67 (6.63, 6.71) | 15.33 (15.25, 15.42) | 25.57 (25.40, 25.75) |
Normal mucosa | 0.44 (0.42, 0.45) | 3.29 (3.24, 3.34) | 6.93 (6.85, 7.01) | 15.77 (15.62, 15.92) | 26.50 (26.19, 26.82) |
Difference | 0.11 (0.10, 0.13) | 0.29 (0.23, 0.34) | 0.26 (0.17, 0.35) | 0.43 (0.28, 0.59) | 0.93 (0.61, 1.25) |
Compared with their siblings b | |||||
HR (95%CIs) | 1.40 (1.33, 1.48) | 1.12 (1.09, 1.15) | 1.05 (1.02, 1.08) | 1.03 (1.00, 1.07) | 1.03 (0.97, 1.08) |
Cumulative incidence (95% CIs), % | |||||
Siblings | 0.20 (0.19, 0.21) | 1.96 (1.92, 2.00) | 4.67 (4.60, 4.74) | 12.13 (11.97, 12.30) | 22.11 (21.75, 22.49) |
Normal mucosa | 0.30 (0.28, 0.32) | 2.41 (2.36, 2.47) | 5.30 (5.20, 5.39) | 12.92 (12.72, 13.13) | 23.00 (22.55, 23.46) |
Difference | 0.10 (0.08, 0.12) | 0.46 (0.39, 0.53) | 0.63 (0.51, 0.74) | 0.79 (0.58, 1.00) | 0.89 (0.42, 1.36) |