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Table 2 Association of sociodemographic factors, clinical factors, and initial symptoms with time from symptom onset to diagnosis in patients with colorectal cancer

From: Relationship between time from symptom’s onset to diagnosis and prognosis in patients with symptomatic colorectal cancer

  1st quartile
 <  = 1.9 month
2nd quartile
1.9–4.2 month
3rd quartile
4.2–8.4 month
4rd quartile
 > 8.4 months
P value
Age median (IQR) years 71 (63.5–78) 72 (63–77) 69 (59.7–77) 74 (62–79) 0.038
Sex: Women 65/193 (33.7) 61/197 (31.0) 88/192 (45.8) 79/193 (40.9) 0.010
Level of education:
  Primary 120/175 (69.0) 128/183 (69.9) 123/181 (68.0) 133/182 (73.1)  
  High school 39/175 (22.4) 45/183 (24.6) 46/181 (25.4) 40/182 (22.0)  
  University 15/175 (8.6) 10/183 (5.5) 12/181 (6.6) 9/182 (4.9) 0.780
Tumor Stage
  0-I 30/176 (17.0) 31/181 (17.1) 35/172 (20.3) 41/172 (23.8)  
  II 65/176 (36.9) 54/181 (29.8) 61/172 (35.5) 46/182 (26.7)  
  III 46/176 (26.1) 56/181 (30.9) 49/172 (28.5) 51/182 (29.7)  
  IV 35/176 (19.9) 40/181 (22.1) 27/172 (15.7) 34/182 (19.8) 0.421
Localization
  Colon 115/194 (59.3) 125/197 (63.5) 113/192 (58.9) 120/195 (61.5)  
  Rectum 79/194 (40.7) 72/197 (36.5) 79/192 (41.1) 75/195 (38.5) 0.782
Tumor grade
  Grade I 37/174 (21.3) 46/192 (24.0) 39/179 (21.8) 44/181 (24.3)  
  Grade II 119/174 (68.4) 123/192 (64.1) 117/179 (65.4) 123/181 (68.0)  
  Grade III/IV 12/174 (6.9) 19/192 (9.9) 18/179 (10.1) 10/181 (5.6)  
  Ungraded 6/174 (3.4) 4/192 (2.1) 5/179 (2.8) 4/181 (2.2 0.825
  Intestinal obstruction 42/192 (21.9) 22/195 (11.3) 24/187 (12.8) 17/190 (8.9) 0.001
  Emergency presentation 130/193 (67.4) 89/197 (45.2) 73/189 (38.6) 64/193 (33.2)  < 0.001
Perception of seriousness
  Not serious 102/157 (65.0) 105/173(60.7) 127/167 (76.0) 124/171 (72.5)  
  Quite serious 37/157 (23.6) 50/173(28.9) 31/167 (18.6) 44/171 (25.7) 0.001
  Very serious 18/157 (11.5) 18/173 (10.4) 9/167 (5.4) 3/171 (1.8)  
Help seeking behavior
  Visit doctor 129/156 (82.7) 125/170 (73.5) 125/176 (71.0) 108/169 (63.9)  
  Wait 27/156 (17.3) 45/170 (26.5) 51/176 (29.0) 61/169 (36.1) 0.002
Charlson index
  Median (IQR) 1 (0–2) 1 (0–2) 0 (0–2) 1 (0–1) 0.237
First symptoms presentations
  Abdominal Pain 59/174 (33.9) 46/179 (25.7) 52/177 (29.4) 37/181 (20.4) 0.033
  Tenesmus 19/174 (10.9) 12/179 (6.7) 17/177 (9.6) 12/181 (6.6) 0.360
  Rectal bleeding 75/174 (43.1) 72/179 (40.2) 66/177 (37.3) 71/181 (39.2) 0.732
  Constipation 35/174 (20.1) 29/179 (16.2) 31/177 (17.5) 18/181 (9.9) 0.058
  Weight loss 14/174 (8.0) 15/179 (8.4) 21/177 (11.9) 7/181 (3.9) 0.050
  Anorexia 15/174 (8.6) 9/179 (5.0) 18/177 (10.2) 7/181 (3.9) 0.062
  Abdominal mass 2/174 (1.1) 3/179 (25.2) 5/177 (2.8) 5/181 (2.8) 0.687
  Tiredness 18/174 (10.3) 25/179 (14.0) 28/177 (15.8) 26/181 (14.4) 0.491