Table 2 Association of sociodemographic factors, clinical factors, and initial symptoms with time from symptom onset to diagnosis in patients with colorectal cancer
1st quartile < = 1.9 month | 2nd quartile 1.9–4.2 month | 3rd quartile 4.2–8.4 month | 4rd quartile > 8.4 months | P value | |
|---|---|---|---|---|---|
Age median (IQR) years | 71 (63.5–78) | 72 (63–77) | 69 (59.7–77) | 74 (62–79) | 0.038 |
Sex: Women | 65/193 (33.7) | 61/197 (31.0) | 88/192 (45.8) | 79/193 (40.9) | 0.010 |
Level of education: | |||||
Primary | 120/175 (69.0) | 128/183 (69.9) | 123/181 (68.0) | 133/182 (73.1) | |
High school | 39/175 (22.4) | 45/183 (24.6) | 46/181 (25.4) | 40/182 (22.0) | |
University | 15/175 (8.6) | 10/183 (5.5) | 12/181 (6.6) | 9/182 (4.9) | 0.780 |
Tumor Stage | |||||
0-I | 30/176 (17.0) | 31/181 (17.1) | 35/172 (20.3) | 41/172 (23.8) | |
II | 65/176 (36.9) | 54/181 (29.8) | 61/172 (35.5) | 46/182 (26.7) | |
III | 46/176 (26.1) | 56/181 (30.9) | 49/172 (28.5) | 51/182 (29.7) | |
IV | 35/176 (19.9) | 40/181 (22.1) | 27/172 (15.7) | 34/182 (19.8) | 0.421 |
Localization | |||||
Colon | 115/194 (59.3) | 125/197 (63.5) | 113/192 (58.9) | 120/195 (61.5) | |
Rectum | 79/194 (40.7) | 72/197 (36.5) | 79/192 (41.1) | 75/195 (38.5) | 0.782 |
Tumor grade | |||||
Grade I | 37/174 (21.3) | 46/192 (24.0) | 39/179 (21.8) | 44/181 (24.3) | |
Grade II | 119/174 (68.4) | 123/192 (64.1) | 117/179 (65.4) | 123/181 (68.0) | |
Grade III/IV | 12/174 (6.9) | 19/192 (9.9) | 18/179 (10.1) | 10/181 (5.6) | |
Ungraded | 6/174 (3.4) | 4/192 (2.1) | 5/179 (2.8) | 4/181 (2.2 | 0.825 |
Intestinal obstruction | 42/192 (21.9) | 22/195 (11.3) | 24/187 (12.8) | 17/190 (8.9) | 0.001 |
Emergency presentation | 130/193 (67.4) | 89/197 (45.2) | 73/189 (38.6) | 64/193 (33.2) | < 0.001 |
Perception of seriousness | |||||
Not serious | 102/157 (65.0) | 105/173(60.7) | 127/167 (76.0) | 124/171 (72.5) | |
Quite serious | 37/157 (23.6) | 50/173(28.9) | 31/167 (18.6) | 44/171 (25.7) | 0.001 |
Very serious | 18/157 (11.5) | 18/173 (10.4) | 9/167 (5.4) | 3/171 (1.8) | |
Help seeking behavior | |||||
Visit doctor | 129/156 (82.7) | 125/170 (73.5) | 125/176 (71.0) | 108/169 (63.9) | |
Wait | 27/156 (17.3) | 45/170 (26.5) | 51/176 (29.0) | 61/169 (36.1) | 0.002 |
Charlson index | |||||
Median (IQR) | 1 (0–2) | 1 (0–2) | 0 (0–2) | 1 (0–1) | 0.237 |
First symptoms presentations | |||||
Abdominal Pain | 59/174 (33.9) | 46/179 (25.7) | 52/177 (29.4) | 37/181 (20.4) | 0.033 |
Tenesmus | 19/174 (10.9) | 12/179 (6.7) | 17/177 (9.6) | 12/181 (6.6) | 0.360 |
Rectal bleeding | 75/174 (43.1) | 72/179 (40.2) | 66/177 (37.3) | 71/181 (39.2) | 0.732 |
Constipation | 35/174 (20.1) | 29/179 (16.2) | 31/177 (17.5) | 18/181 (9.9) | 0.058 |
Weight loss | 14/174 (8.0) | 15/179 (8.4) | 21/177 (11.9) | 7/181 (3.9) | 0.050 |
Anorexia | 15/174 (8.6) | 9/179 (5.0) | 18/177 (10.2) | 7/181 (3.9) | 0.062 |
Abdominal mass | 2/174 (1.1) | 3/179 (25.2) | 5/177 (2.8) | 5/181 (2.8) | 0.687 |
Tiredness | 18/174 (10.3) | 25/179 (14.0) | 28/177 (15.8) | 26/181 (14.4) | 0.491 |