Table 4 Analysis for TTR and DFS for combined genetic and immune variables

CTNNB1 Mutation + CD8+ (TC)

CTNNB1(−)/CD8TC(LD)

9

1.00

1.00

CTNNB1(+)/CD8TC(HD)

17

0.12 (0.03–0.52, p = 0.005)

0.25 (0.09–0.74, p = 0.012)

CTNNB1 Mutation + CD8+ (IM)

CTNNB1(−)/CD8TIM(LD)

11

1.00

1.00

CTNNB1(+)/CD8TIM(HD)

18

0.17 (0.05–0.59, p = 0.005)

0.34 (0.13–0.87, p = 0.025)

rs2853669 + CD8+ (TC)

AA/CD8TC(LD)

5

1.00

1.00

AA/CD8TC(HD)

23

0.51 (0.14–1.92, p = 0.319)

0.53 (0.17–1.64, p = 0.271)

GG/CD8TC(LD)

3

0.91 (0.15–5.46, p = 0.913)

1.00 (0.22–4.52, p = 0.995)

GG/CD8TC(HD)

12

0.10 (0.02–0.62, p = 0.013)

0.19 (0.05–0.69, p = 0.011)

rs2853669 + CD8+ (IM)

AA/CD8TIM(LD)

8

1.00

1.00

AA/CD8TIM(HD)

19

0.75 (0.24–2.33, p = 0.614)

0.69 (0.28–1.70, p = 0.416)

GG/CD8TIM(LD)

2

1.07 (0.12–9.29, p = 0.953)

0.69 (0.09–5.59, p = 0.728)

GG/CD8TIM(HD)

13

0.17 (0.04–0.71, p = 0.015)

0.22 (0.08–0.61, p = 0.003)

TERTp mutation (−124 bp) + rs2853669

TERTp(−)/AA

8

1.00

1.00

TERTp(+)/AA

17

0.38 (0.12–1.16, p = 0.089)

0.43 (0.16–1.15, p = 0.092)

TERTp(−)/GG

5

0.08 (0.01–0.72, p = 0.024)

0.23 (0.06–0.82, p = 0.024)

TERTp(+)/GG

10

0.15 (0.03–0.62, p = 0.009)

0.20 (0.06–0.64, p = 0.007)