Table 3 Univariable analysis of genetic and immune variables associated with TTR and DFS
Variable | TTR | DFS | ||
|---|---|---|---|---|
Group | N | HR | HR | |
TERTp mutation (124 bp) | WT | 17 | 1.00 | 1.00 |
MT | 41 | 0.62 (0.27–1.40, p = 0.248) | 0.72 (0.37–1.40, p = 0.335) | |
TERTp mutation (146 bp) | WT | 61 | 1.00 | 1.00 |
MT | 3 | 1.88 (0.44–8.02, p = 0.392) | 2.00 (0.61–6.55, p = 0.252) | |
CTNNB1 Mutation | WT | 38 | 1.00 | 1.00 |
MT | 21 | 0.31 (0.11–0.83, p = 0.020) | 0.57 (0.28–1.16, p = 0.121) | |
rs2853669 | A/A | 30 | 1.00 | 1.00 |
A/G | 22 | 0.73 (0.33–1.63, p = 0.443) | 0.71 (0.36–1.40, p = 0.330) | |
G/G | 15 | 0.29 (0.09–0.88, p = 0.028) | 0.42 (0.20–0.90, p = 0.025) | |
CD8 TC | LD | 16 | 1.00 | 1.00 |
HD | 49 | 0.32 (0.14–0.71, p = 0.005) | 0.41 (0.21–0.80, p = 0.009) | |
CD8 IM | LD | 16 | 1.00 | 1.00 |
HD | 48 | 0.34 (0.15–0.78, p = 0.011) | 0.37 (0.19–0.73, p = 0.004) |