Multiparameter diagnostic model based on 18F-FDG PET and clinical characteristics can differentiate thymic epithelial tumors from thymic lymphomas

Table 3 Differential diagnostic efficiency of ¹⁸F-FDG PET/CT parameters between thymic epithelial tumors and thymic lymphomas

Parameters	Cut-off	AUC (95%CI)	Sensitivity (95%CI)	Specificity (95%CI)	PPV (95%CI)	NPV (95%CI)
Lesion size (mm)	74.5	0.775 (0.704–0.845)	0.763 (0.662–0.843)	0.725 (0.612–0.816)	0.763 (0.662–0.843)	0.725 (0.612–0.816)
SUVmax	10.5	0.845 (0.787–0.903)	0.742 (0.639–0.825)	0.850 (0.749–0.917)	0.852 (0.752–0.918)	0.739 (0.635–0.823)
SUVmean	6.2	0.835 (0.775–0.895)	0.688 (0.583–0.778)	0.863 (0.763–0.926)	0.853 (0.748–0.921)	0.704 (0.602–0.790)
TLG	626.7	0.822 (0.753–0.884)	0.688 (0.583–0.778)	0.850 (0.749–0.917)	0.842 (0.736–0.912)	0.701 (0.598–0.788)
MTV	113.9	0.730 (0.655–0.805)	0.624 (0.517–0.720)	0.775 (0.665–0.858)	0.763 (0.649–0.850)	0.639 (0.535–0.732)
SUVR	6.2	0.881 (0.831–0.932)	0.763 (0.662–0.843)	0.888 (0.792–0.944)	0.888 (0.792–0.944)	0.763 (0.662–0.843)

CI Confidence interval, SUVmax Max standard uptake value, SUVmean Mean standard uptake value, MTV Metabolic tumor volume, TLG Total lesion glycolysis, AUC Area under the curve, PPV Positive predictive value, NPV Negative predictive value, SUVR Standard uptake value ratio

ISSN: 1471-2407