Table 2 Relationship between cleaved caspase-3 (CC3) staining and clinicopathological parameters in oesophageal adenocarcinoma patients. Statistical analysis was carried out using chi-squared test (* p < 0.05)
Cleaved Caspase-3 | |||
|---|---|---|---|
Negative n=123 | Positive n=21 | p–value | |
Differentiation (unknown n = 2) | |||
Well | 6 (5%) | 0 (0%) | 0.034* |
Moderate | 40 (33.1%) | 13 (61.9%) | |
Poor | 75 (62.0%) | 8 (38.1%) | |
Histological T staging | |||
T I | 14 (11.4%) | 3 (14.3%) | |
T II | 20 (16.3%) | 7 (33.3%) | |
T III | 84 (68.3%) | 11 (52.4%) | |
T IV | 5 (4.1%) | 0 (0%) | 0.216 |
Clinical T staging (unknown n = 12) | |||
T I | 3 (2.7%) | 0 (0%) | |
T II | 8 (7.2%) | 3 (14.3%) | |
T III | 98 (88.3%) | 18 (85.7%) | |
T IV | 2 (1.8%) | 0 (0%) | 0.568 |
Lympho-vascular invasion (unknown n = 2) | |||
Negative | 39 (32.2%) | 10 (47.6%) | 0.171 |
Positive | 82 (67.8%) | 11 (52.4%) | |
Recurrence | |||
Negative | 51 (61.0%) | 14 (66.7%) | 0.032* |
Positive | 72 (58.5%) | 7 (33.3%) | |
Mandard (unknown n = 8) | |||
Response N=10 | 10 (8.2%) | 0 (0%) | 0.245 |
No response N=126 | 107 (87.7%) | 19 (90.5%) | |