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Table 4 Multivariate analysis of factors associated with long-term outcomes (n = 44)

From: Outcomes of allogeneic haematopoietic stem cell transplantation for paediatric patients with MLL-rearranged acute myeloid leukaemia

Items OS EFS CIR
  HR(95%CI) P HR(95%CI) P HR(95%CI) P
MRD + at pre-HSCT 5.83(1.52–22.29) 0.01 4.47(1.48–13.48) 0.01 6.44(1.61–25.74) 0.01
II-IV aGVHD 2.39(0.69–8.25) 0.17 3.57(1.08–11.8) 0.04 3.13(0.70–13.95) 0.13
1 cycle to CR 0.61(0.18–2.02) 0.42 0.29(0.09–0.97) 0.04 0.24(0.05–1.05) 0.06
CNS infiltration    1.32(0.33–5.31) 0.69 2.51(0.50–12.62) 0.26
  1. OS overall survival; EFS: event-free survival, CIR cumulative incidence of relapse, MRD + Minimal Residual Disease-positive, aGVHD Acute graft versus host disease, CNS central nervous system