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Table 4 Multivariate analysis of factors associated with long-term outcomes (n = 44)

From: Outcomes of allogeneic haematopoietic stem cell transplantation for paediatric patients with MLL-rearranged acute myeloid leukaemia

Items

OS

EFS

CIR

 

HR(95%CI)

P

HR(95%CI)

P

HR(95%CI)

P

MRD + at pre-HSCT

5.83(1.52–22.29)

0.01

4.47(1.48–13.48)

0.01

6.44(1.61–25.74)

0.01

II-IV aGVHD

2.39(0.69–8.25)

0.17

3.57(1.08–11.8)

0.04

3.13(0.70–13.95)

0.13

1 cycle to CR

0.61(0.18–2.02)

0.42

0.29(0.09–0.97)

0.04

0.24(0.05–1.05)

0.06

CNS infiltration

  

1.32(0.33–5.31)

0.69

2.51(0.50–12.62)

0.26

  1. OS overall survival; EFS: event-free survival, CIR cumulative incidence of relapse, MRD + Minimal Residual Disease-positive, aGVHD Acute graft versus host disease, CNS central nervous system
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BMC Cancer

ISSN: 1471-2407

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