Table 1 Main characters of the studies included in the meta-analysis [15,16,17,18,19,20,21]
Authors | Year | District | Study design | participants | Reference standard | Detection method | Biomarkers | TP | FP | TN | FN |
|---|---|---|---|---|---|---|---|---|---|---|---|
Lin et al. | 2018 | Taiwan | Prospective | 48 | Cytopathologically | Immunofluorescence | EpCAM、TSHR | 22 | 2 | 4 | 20 |
Xu et al. | 2016 | USA | Prospective | 42 | Medical image | CellSearch | EpCAM | 13 | 0 | 19 | 10 |
Tseng et al. | 2017 | Taiwan | Prospective | 77 | Medical image | immunofluorescence | EpCAM | 27 | 2 | 5 | 43 |
Li et al. | 2018 | Taiwan | Prospective | 25 | Medical image | immunofluorescence | EpCAM、TSHR | 6 | 0 | 1 | 18 |
Qiu et al. | 2018 | China | Prospective | 72 | Pathological、medical image | immunofluorescence | EpCAM | 19 | 7 | 11 | 35 |
Winken et al. | 2014 | Germany | Prospective | 14 | Tg、Medical image | immunofluorescence | EpCAM | 1 | 4 | 1 | 8 |
Lin et al. | 2015 | Taiwan | Prospective | 29 | Biochemical、medical image | immunofluorescence | EpCAM、TSHR | 16 | 2 | 2 | 9 |