Table 2 Corresponding particulars of mutations occurring in KPNA2 and their frequency as located in cBioportal. TCGA: The Cancer Genome Atlas Program Pan-Cancer Atlas [31] and the MBC: Metastatic Breast Cancer Project [26]
From: Evaluation of the role of KPNA2 mutations in breast cancer prognosis using bioinformatics datasets
Protein change | Mutation type | No. of mutations | Variant frequency | Original study |
|---|---|---|---|---|
R366H | Missense | 1250 | 0.23 | TCGA |
N375S | Missense | 972 | 0.24 | TCGA |
L382F | Missense | 832 | 0.07 | TCGA |
S24N | Missense | 123 | 0.06 | MBC |
V507A | Missense | 30 | 0.28 | MBC |
D79N | Missense | 107 | 0.23 | TCGA |
Q329del | Deletion | 36 | 0.30 | TCGA |
R29C | Missense | 35 | N/A | TCGA |