Factors associated with initiation and continuation of endocrine therapy in women with hormone receptor-positive breast cancer

Table 1 Patient characteristics of racial minorities by the study samples

	Cohort Black/other	RCT Black	P value^d
Total	65	157
Age, years			0.08
Mean (SD)	58.9 (11.4)	56.2 (10.0)
Insurance status			< 0.01
Private	42 (64.6%)	67 (42.7%)
Public only or other^a	23 (35.4%)	90 (57.3%)
Chemotherapy			0.08
No	47 (72.3%)	94 (59.9%)
Yes	18 (27.7%)	63 (40.1%)
Radiation therapy			< 0.01
No	28 (43.1%)	35 (22.3%)
Yes	37 (56.9%)	122 (77.7%)
Diabetes			0.05
No	54 (83.1%)	111 (70.7%)
Yes	11 (16.9%)	46 (29.3%)
Obesity			0.80
No (BMI < 30 kg/m²)	26 (40.0%)	60 (38.2%)
Yes (BMI ≥ 30 kg/m²)	39 (60.0%)	97 (61.8%)
Elevated depressed mood			0.01
No (CESD < 16)	53 (81.5%)	101 (64.3%)
Yes (CESD ≥16)	12 (18.5%)	56 (35.7%)
Menopausal-symptom severity, mean (SD)	1.8 (0.9)	1.9 (0.9)	0.46
ET initiation^b			0.32
No	11 (16.9%)	36 (22.9%)
Yes	54 (83.1%)	121 (77.1%)
ET continuation^c			0.10
No	5 (9.4%)	23 (19.3%)
Yes	48 (90.6%)	96 (80.7%)

RCT randomized controlled trial, ET endocrine therapy, SD standard deviation, BMI body mass index, CESD Center for Epidemiologic Studies Depression scale
^a Other insurance status includes no insurance or self-pay
^b ET initiated by the 12-month interview
^c ET continued for at least 12 months after initiation. Of 175 patients of racial minorities who initiated ET within first 12 months, three were excluded due to missing data for obesity (n = 2, one from the cohort study and the other one from the RCT) and diabetes (n = 1 from the RCT)
^d Differences between the cohort study and the RCT in continuous variables were tested with the independent-samples t-test, and differences in categorical variables were tested with Chi-square test

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