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Table 3 Associations of IFT20 and GM130 protein expressions with clinicopathological features of patients with lung adenocarcinoma

From: Associations of IFT20 and GM130 protein expressions with clinicopathological features and survival of patients with lung adenocarcinoma

Proteins

D Value

Differentiated types

Tumor size

TNM stage

Lymphatic metastasis

Distant metastasis

Poorly/moderately to well

OR(95%CI)

> 7 cm/≤7 cm

OR(95%CI)

II ~ IV/I

OR(95%CI)

Yes/No

OR(95%CI)

Yes/No

OR(95%CI)

IFT20

IOD/area

71/164

0.96 (0.72, 1.28)

25/210

0.71 (0.46, 1.09)

183/52

0.84 (0.62, 1.16)

145/90

0.82 (0.63, 1.08)

47/188

1.01 (0.72, 1.41)

 

 Q1(<−0.006)

20/38

reference

8/50

reference

49/9

reference

37/21

reference

13/45

reference

 

 Q2(−0.006 ~ 0.0207)

14/45

0.57 (0.25, 1.29)

8/51

0.92 (0.30, 2.82)

49/10

0.82 (0.31, 2.23)

40/19

1.13 (0.52, 2.45)

12/47

0.82 (0.33, 2.05)

 

 Q3(0.0207 ~ 0.052)

18/42

0.85 (0.39, 1.87)

5/55

0.60 (0.17, 2.05)

42/18

0.44 (0.17, 1.04)

36/24

0.81 (0.38, 1.72)

9/51

0.62 (0.24, 1.63)

 

 Q4(> 0.052)

19/39

0.97 (0.44, 2.12)

4/54

0.39 (0.10, 1.47)

43/15

0.50 (0.20, 1.28)

32/26

0.65 (0.30, 1.38)

13/45

0.95 (0.38, 2.34)

 

 Ptrend

0.922

 

0.131

 

0.080

 

0.186

 

0.823

 
 

Rate of positive cells

71/164

1.00 (0.98, 1.01)

25/210

1.00 (0.97, 1.02)

183/52

0.99 (0.97, 1.01)

145/90

0.99 (0.97, 1.01)

47/188

0.99 (0.97, 1.01)

 

 Q1(< 3.096)

17/41

reference

5/53

reference

49/9

reference

40/18

reference

15/43

reference

 

 Q2(3.096 ~ 12.466)

20/40

1.27 (0.58, 2.79)

6/54

1.17 (0.32, 4.27)

46/14

0.58 (0.23, 1.48)

35/25

0.63 (0.30, 1.34)

11/49

0.68 (0.27, 1.68)

 

 Q3(12.466 ~ 22.828)

21/37

1.41 (0.64, 3.10)

10/48

2.39 (0.73, 7.86)

47/12

0.67 (0.26, 1.77)

41/17

1.09 (0.49, 2.40)

10/48

0.57 (0.23, 1.43)

 

 Q4(> 22.828)

13/46

0.72 (0.31, 1.67)

4/55

0.76 (0.18, 3.16)

41/17

0.40 (0.16, 1.01)

29/30

0.44 (0.20, 0.93)

11/48

0.61 (0.24, 1.51)

 

 Ptrend

0.414

 

0.912

 

0.086

 

0.07

 

0.331

 
 

Staining intensity score

71/164

0.99 (0.74, 1.34)

25/210

0.66 (0.44, 1.01)

183/52

0.68 (0.47, 0.96)

145/90

0.71 (0.53, 0.94)

47/188

0.82 (0.59, 1.14)

GM130

IOD/area

71/164

0.97 (0.73, 1.29)

25/210

0.82 (0.56, 1.20)

183/52

1.10 (0.82, 1.48)

145/90

0.97 (0.74, 1.27)

47/188

1.13 (0.78, 1.63)

 

 Q1(<−0.031)

23/36

reference

11/48

reference

48/11

reference

39/20

reference

7/52

reference

 

 Q2(−0.031 ~ − 0.014)

15/45

0.52 (0.24, 1.14)

3/57

0.14 (0.03, 0.60)

46/14

0.67 (0.27, 1.66)

38/22

0.81 (0.37, 1.74)

13/47

1.88 (0.67, 5.29)

 

 Q3(−0.014 ~ 0.005)

20/37

0.85 (0.40, 1.80)

3/54

0.23 (0.06, 0.92)

43/14

0.75 (0.30, 1.88)

35/22

0.82 (0.38, 1.77)

12/45

2.10 (0.74, 5.92)

 

 Q4(> 0.005)

13/46

0.44 (0.20, 0.99)

8/51

0.44 (0.15, 1.33)

46/13

0.70 (0.28, 1.78)

33/26

0.57 (0.27, 1.23)

15/44

2.06 (0.75, 5.66)

 

 Ptrend

0.102

 

0.204

 

0.508

 

0.226

 

0.17

 
 

Rate of positive cells

71/164

0.97 (0.95,0.99)

25/210

0.97 (0.94, 1.01)

183/52

1.00 (0.98, 1.03)

145/90

0.99 (0.98, 1.02)

47/188

1.00 (0.98, 1.03)

 

 Q1(<−6.377)

23/36

reference

10/49

reference

48/10

reference

38/21

reference

12/47

reference

 

 Q2(−6.377 ~ −0.164)

22/36

1.01 (0.48, 2.15)

4/54

0.28 (0.08, 1.03)

48/12

0.78 (0.31, 1.99)

40/18

1.23 (0.57, 2.65)

13/45

1.05 (0.42, 2.63)

 

 Q3(−0.164 ~ 7.683)

13/47

0.42 (0.19, 0.95)

5/55

0.33 (0.10, 1.08)

39/20

0.38 (0.16, 0.92)

29/31

0.52 (0.25, 1.08)

9/51

0.71 (0.26, 1.88)

 

 Q4(> 7.683)

13/45

0.48 (0.21, 1.09)

6/52

0.45 (0.14, 1.45)

48/10

0.95 (0.36, 2.51)

38/20

1.05 (0.49, 2.25)

13/45

1.02 (0.41, 2.54)

 

 Ptrend

0.024

 

0.294

 

0.897

 

0.073

 

0.948

 
 

Staining intensity score

71/164

0.71 (0.55, 0.91)

25/210

0.62 (0.41, 0.93)

183/52

0.95 (0.72, 1.26)

145/90

0.79 (0.62, 1.01)

47/188

1.03 (0.77, 1.38)

  1. Estimates were adjusted for age, gender, smoking status, and smoking amounts.