Fig. 8
From: Genomic signature of MTOR could be an immunogenicity marker in human colorectal cancer
Mutation profiles of MTOR in MSI and MSS CRC. A, B Cohort summary plots of the MSI-H and MSS CRC patients displaying the distribution of variants in MTOR according to variant classification, type and SNV class. The bottom part (from left to right) indicates the mutation load for each sample, and variant classification type. C The differences in the distribution of variant classification among MTOR mutations between MSI and MSS CRC patients. D The differences in the distribution of variant type among MTOR mutations between MSI and MSS CRC patients. E The differences in the distribution of SNVs among MTOR mutations between MSI and MSS CRC patients. F The differences in the distribution of transition (Ti) and transversion (Tv) among MTOR mutations between MSI and MSS CRC patients. ns, not significant, *p < 0.05, **p < 0.01. CRC, colorectal cancer; MSI, microsatellite instability; MSI-H, MSI-high; MSS; microsatellite stable; SNV, single-nucleotide variant