Fig. 5

Statistics describing mutation and TMB between low and high MTOR expression groups. A, B Cohort summary plots of the low and high MTOR expression groups displaying the distribution of variants according to variant classification, type and SNV class. The bottom part (from left to right) indicates the mutation load for each sample, and variant classification type. A stacked barplot shows the top ten mutated genes. C, D The oncoplots show the different mutation information between the low and high MTOR expression groups. E The forest plot displays differentially mutated genes between the high and low MTOR expression groups. Bars indicate the 95% confidence interval for the odds ratio. The adjacent table includes the number of patients in the high and low MTOR expression groups with the mutations in the highlighted gene. ***p < 0.001. F The boxplot shows differences in TMB between high and low MTOR expression groups. TMB, tumor mutational burden; CRC colorectal cancer