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Fig. 4 | BMC Cancer

Fig. 4

From: Genomic signature of MTOR could be an immunogenicity marker in human colorectal cancer

Fig. 4

Somatic mutation profiles in CRC. A Cohort summary plot of the mutation information among 537 CRC patients from TCGA displaying the distribution of variants according to variant classification, type, and SNV class. The bottom part (from left to right) indicates the mutation load for each sample, and variant classification type. A stacked barplot shows the top ten mutated genes. B The oncoplot displays the mutation information of the CRC cohort. Genes are ordered by their mutation frequency. C The oncoplot shows the mutation information of genes associated with the mTOR pathway. CRC, colorectal cancer; TCGA, The Cancer Genome Atlas, mTOR, mammalian target of rapamycin

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