Fig. 3
From: Genomic signature of MTOR could be an immunogenicity marker in human colorectal cancer
Identification of MTOR-related DEGs in CRC and enrichment pathway analysis. A, B The heatmap and volcano plot show DEGs between low and high MTOR expression groups in CRC patients; “down” and blue dots indicate downregulated DEGs; “up” and red dots indicate upregulated DEGs; “stable” indicates that the difference was not significant. C The top 15 pathways involved in DEGs by KEGG. D The top 15 functions involved in DEGs by GO enrichment analysis. The GSEA results show differentially enriched terms involved in DEGs. E “ECM-receptor interaction”, F “focal adhesion”, G “regulation of actin cytoskeleton”, H “adherens junction”, I “ribosome”, J “oxidative phosphorylation”, K “fatty acid metabolism”, and (L) “glutathione metabolism”. DEGs, differentially expressed genes; CRC, colorectal cancer; KEGG, Kyoto Encyclopedia of Genes and Genomes; GO, Gene Ontology; GSEA, gene set enrichment analysis