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Table 2 Correlations between patient characteristics and MSI status in CRC patients

From: Metabolic activity via 18F-FDG PET/CT is predictive of microsatellite instability status in colorectal cancer

 

CRC with MSI-H(n = 44)

CRC with MSS(n = 376)

P value

Age, years, median, (range)

56.5(24–84)

61(18–87)

0.048*

Male: female ratio

29:15

225:151

0.436#

Primary lesion (right: left hemi-colon)

26:18

92:284

< 0.001#

Histologic grade (poorly/moderately-poorly: moderately /highly)

11:31

45:309

0.018#

Mucinous carcinoma (yes: no)

3:50

31:338

0.686#

T stage (T2–3: T4)

39:12

260:108

0.152#

N stage (N0: N1–2)

26:25

148:220

0.225#

M stage (M0: M1)

45:7

287:80

0.507#

SUVmax, median(range)

13.81(5.97–47.06)

13.78(4.10–54.73)

0.502*

SUVmean, median(range)

7.29(3.67–16.22)

7.95(2.81–22.70)

0.319*

MTV, median(range)

33.60(1.34–183.42)

18.08(1.86–391.04)

0.004*

TLG, median(range)

229.03(5.36–1540.76)

134.26(7.25–2634.39)

0.010*

  1. SUVmax the maximum standardized uptake values, SUVmean mean standardized uptake values, MTV metabolic tumor volume, TLG total lesion glycolysis
  2. p values were calculated using the *Mann–Whitney U-test and #χ2 test