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Table 3 Performances of POSTN in diagnosis of CA153-negative and CEA- negative BCa patients

From: Soluble POSTN is a novel biomarker complementing CA153 and CEA for breast cancer diagnosis and metastasis prediction

Analysis groups

AUC (95% CI)

Cut-off value

Sensitivity (%)

Specificity (%)

Healthy vs. BCa CA153-negative

  POSTN

0.72 (0.65 – 0.79)

14.2

70.5

70.0

  CEA

0.65 (0.57 – 0.72)

1.8

55.3

75.0

Healthy vs. BCa CEA-negative

  POSTN

0.75 (0.68 – 0.81)

14.5

70.1

71.7

  CA153

0.63 (0.56 – 0.70)

20.3

32.3

93.3