Table 2 Age-standardized incidence rates (ASR) per 100,000 person-years with 95% confidence intervals (CIs) of pediatric CNS tumors in Finland 1990–2017
From: Incidence trends of childhood central nervous system tumors in Finland 1990–2017
Total | Boys | Girls | ||||
|---|---|---|---|---|---|---|
N (%) | ASR (95% CI) | N (%) | ASR (95% CI) | N (%) | ASR (95% CI) | |
Total | 1117 (100) | 4.30 (4.26, 4.34) | 614 (100) | 4.63 (4.57, 4.69) | 503 (100) | 3.96 (3.91, 4.02) |
Age group | ||||||
0–4 years | 428 (38) | 5.08 (4.60, 5.56) | 242 (39) | 5.62 (4.91, 6.33) | 186 (37) | 4.51 (3.86, 5.16) |
5–9 years | 363 (33) | 4.20 (3.77, 4.63) | 200 (33) | 4.53 (3.90, 5.16) | 163 (32) | 3.85 (3.26, 4.45) |
10–14 years | 326 (29) | 3.70 (3.30, 4.10) | 172 (28) | 3.82 (3.25, 4.39) | 154 (31) | 3.57 (3.01, 4.13) |
Tumor grade | ||||||
Grade I | 531 (48) | 2.05 (2.02, 2.08) | 285 (46) | 2.15 (2.11, 2.19) | 246 (49) | 1.94 (1.90, 1.98) |
Grade II | 155 (14) | 0.60 (0.58, 0.61) | 80 (13) | 0.60 (0.58, 0.62) | 75 (15) | 0.59 (0.57, 0.61) |
Grade III | 99 (9) | 0.38 (0.37, 0.39) | 53 (9) | 0.40 (0.38, 0.41) | 46 (9) | 0.36 (0.35, 0.38) |
Grade IV | 246 (22) | 0.95 (0.93, 0.97) | 152 (25) | 1.14 (1.11, 1.17) | 94 (19) | 0.74 (0.72, 0.77) |
Grade NA | 86 (8) | 0.33 (0.32, 0.34) | 44 (7) | 0.33 (0.31, 0.34) | 42 (8) | 0.33 (0.31, 0.34) |
Tumor location | ||||||
Supratentorial | 349 (31) | 1.34 (1.32, 1.37) | 178 (29) | 1.34 (1.31, 1.38) | 171 (34) | 1.35 (1.31, 1.38) |
Infratentorial | 468 (42) | 1.80 (1.77, 1.83) | 262 (43) | 1.97 (1.93, 2.01) | 206 (41) | 1.62 (1.59, 1.66) |
Cerebellum | 324 (29) | 1.24 (1.22, 1.27) | 185 (30) | 1.39 (1.36, 1.42) | 139 (28) | 1.09 (1.06, 1.12) |
Brain stem | 138 (12) | 0.53 (0.52, 0.55) | 77 (13) | 0.58 (0.56, 0.60) | 61 (12) | 0.48 (0.46, 0.50) |
Spinal cord | 66 (6) | 0.25 (0.24, 0.26) | 42 (7) | 0.32 (0.30, 0.33) | 24 (5) | 0.19 (0.18, 0.20) |
Meninges | 26 (2) | 0.10 (0.09, 0.11) | 15 (2) | 0.11 (0.10, 0.12) | 11 (2) | 0.09 (0.08, 0.10) |
Unspecified | 208 (19) | 0.80 (0.78, 0.82) | 117 (19) | 0.88 (0.85, 0.91) | 91 (18) | 0.72 (0.69, 0.74) |
Histology | ||||||
Diffuse astrocytic tumors | 161 (14) | 0.62 (0.61, 0.64) | 72 (12) | 0.55 (0.52, 0.57) | 89 (18) | 0.71 (0.68, 0.73) |
Other astrocytic tumors | 374 (33) | 1.44 (1.42, 1.46) | 192 (31) | 1.45 (1.42, 1.48) | 182 (36) | 1.43 (1.40, 1.47) |
Pilocytic astrocytoma | 339 (30) | 1.30 (1.28, 1.33) | 176 (29) | 1.33 (1.30, 1.36) | 163 (32) | 1.28 (1.25, 1.31) |
Ependymal tumors | 85 (8) | 0.33 (0.31, 0.34) | 54 (9) | 0.40 (0.39, 0.42) | 31 (6) | 0.24 (0.23, 0.26) |
Neuronal/glial tumors | 118 (11) | 0.46 (0.44, 0.47) | 65 (11) | 0.49 (0.47, 0.51) | 53 (11) | 0.42 (0.40, 0.44) |
Embryonal tumors | 190 (17) | 0.73 (0.71, 0.74) | 123 (20) | 0.92 (0.89, 0.95) | 67 (13) | 0.53 (0.51, 0.55) |
Medulloblastoma | 116 (10) | 0.45 (0.43, 0.46) | 74 (12) | 0.56 (0.54, 0.58) | 42 (8) | 0.33 (0.32, 0.35) |
Other tumors | 189 (17) | 0.73 (0.71, 0.74) | 108 (18) | 0.81 (0.79, 0.84) | 81 (16) | 0.64 (0.61, 0.66) |