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Table 1 Baseline characteristics of the rectal cancer patients before and after propensity score matching

From: Preoperative chemoradiotherapy with capecitabine and triweekly oxaliplatin versus capecitabine monotherapy for locally advanced rectal cancer: a propensity-score matched study

 

Baseline

After propensity score matching

 

Triweekly XELOX n = 277

Capecitabine n = 533

SMD

TriweeklyXELOX n = 191

Capecitabine n = 319

SMD

Age (years) median (range)

55 (24–79)

58 (24–84)

− 0.259

56 (24–79)

56 (24–84)

0.006

Gender

 Male

184 (66.4%)

346 (64.9%)

 

124 (64.9%)

201 (63.0%)

 

 Female

93 (33.6%)

187 (35.1%)

0.032

67 (35.1%)

118 (37.0%)

0.040

Treatment period

 2007–2011

108 (39.0%)

2 (0.4%)

 

52 (27.2%)

2 (0.6%)

 

 2012–2017

169 (61.0%)

531 (99.6%)

−0.792

139 (72.8%)

317 (99.4%)

−0.598

Clinical stage

 II

29 (10.5%)

34 (6.4%)

 

15 (7.9%)

26 (8.2%)

 

 III

248 (89.5%)

499 (93.6%)

−0.133

176 (92.1%)

293 (91.8%)

0.011

cT stage

 cT2

25 (9.0%)

10 (1.9%)

 

8 (4.2%)

6 (1.9%)

 

 cT3

102 (36.8%)

222 (41.7%)

 

73 (38.2%)

136 (42.6%)

 

 cT4

150 (54.2%)

301 (56.5%)

−0.145

110 (57.6%)

177 (55.5%)

−0.004

cN stage

 cN-

29 (10.5%)

34 (6.4%)

 

15 (7.9%)

26 (8.2%)

 

 cN+

248 (89.5%)

499 (93.6%)

−0.134

176 (92.1%)

293 (91.8%)

0.011

Type of Radiation

 3D-CRT

134 (48.4%)

88 (16.5%)

 

50 (26.2%)

77 (24.1%)

 

 IMRT

143 (51.6%)

445 (83.5%)

−0.638

141 (73.8%)

242 (75.9%)

−0.046

RT dose

  < 45 Gy

1 (0.4%)

0 (0.0%)

 

1 (0.5%)

0 (0.0%)

 

 45Gy–50Gy

22 (7.9%)

8 (1.5%)

 

10 (5.2%)

4 (1.3%)

 

 50Gy/50.4 Gy

254 (91.7%)

525 (98.5%)

−0.370

180 (94.2%)

315 (98.7%)

−0.305

Interval from RT to surgery (weeks), median (range)

8 (4–20)

9 (4.3–19.9)

−0.543

8.6 (3.9–20)

9 (4.3–19.9)

−0.107

Type of Surgery

 Abdominoperineal resection

29 (10.5%)

58 (10.9%)

 

21 (11.0%)

35 (11.0%)

 

 Anterior resection

240 (86.6%)

468 (87.8%)

 

165 (86.4%)

280 (87.8%)

 

 Other

8 (2.9%)

7 (1.3%)

0.056

5 (2.6%)

4 (1.3%)

0.037

Adjuvant chemotherapy

 Yes

226 (81.6%)

404 (75.8%)

 

149 (78.0%)

243 (76.2%)

 

 No

51 (18.4%)

129 (24.2%)

0.149

42 (22.0%)

76 (23.8%)

0.044

  1. SMD Standardized mean difference, RT Radiotherapy, 3D-CRT 3-dimensional conformal radiotherapy, IMRT Intensity modulated radiotherapy