Fig. 6From: The importin beta superfamily member RanBP17 exhibits a role in cell proliferation and is associated with improved survival of patients with HPV+ HNSCCRanBP17 localizes to nuclear bodies distinct from SC35 domains. UM-SCC-3 and UT-SCC-26A cells were co-stained with the RanBP17-specific antibody HPA029568 and a SC35-specific antibody (clone SC-35), exhibiting a distinct nuclear localization of RanBP17 (arrowheads) that is different from SC35 domains. DAPI was used to counterstain the nucleus. TP53 mutation in UM-SCC-3: p.R248Q (nuclear p53); TP53 mutation in UT-SCC-26A: p.Y236* (cytoplasmic p53)Back to article page