Fig. 3
Course of RanBP17 expression in HCT116p53wt/wt and UM-SCC-3 tumor cells after CDDP treatment. A RanBP17 RNA expression at different CDDP concentrations (0, 0.78, 1.56, 3.13, 6.25, 12.5, 25, 50, 100 µmol/L) is shown for HCT116p53wt/wt cells using 11 different primer pairs (B). The same is shown for the UM-SCC-3 cell line (C). Here only 3 primer pairs (P3, P5, P11) amplified PCR products. Background information for primer pairs P1-P11 are depicted in Supplementary Fig. S4. Statistical tests: One way ANOVA with Tukey´s correction for multiple comparisons (n=1-6) *p<0.05; **p<0.01; ****p<0.0001