Table 1 Summary of CTC measurements
Characteristic | N | All Patients (n=96) | Neoadjuvant CRT Arm (n=47) | Adjuvant CRT Arm (n=49) | p-value |
|---|---|---|---|---|---|
Any CTCsa– n(%) | |||||
 Any | 74 | 27 (36.5) | 13 (37.1) | 14 (35.9) | 0.912 |
 Baseline | 72 | 16 (22.2) | 9 (26.5) | 7 (18.4) | 0.412 |
 6 months | 53 | 6 (11.3) | 5 (20.0) | 1 (3.6) | 0.089 |
 1 year | 48 | 11 (22.9) | 5 (23.8) | 6 (22.2) | > 0.99 |
 2 years | 29 | 6 (20.7) | 4 (26.7) | 2 (14.3) | 0.651 |
CTC count – mean ± SD | |||||
 Baseline | 72 | 6.5 ± 45.1 | 2.1 ± 9.6 | 10.5 ± 61.6 | 0.504 |
 6 months | 53 | 0.7 ± 2.8 | 1.0 ± 2.9 | 0.5 ± 2.8 | 0.078 |
 1 year | 48 | 2.4 ± 14.0 | 4.9 ± 21.1 | 0.4 ± 1.0 | 0.888 |
 2 years | 29 | 5.1 ± 17.0 | 9.7 ± 23.0 | 0.2 ± 0.6 | 0.309 |
CTC count change – mean ± SD | |||||
 6 months vs. baseline | 51 | 0.2 ± 3.1 | 0.5 ± 2.7 | 0.0 ± 3.4 | 0.488 |
 1 year vs. baseline | 46 | 1.9 ± 13.5 | 4.5 ± 20.4 | -0.1 ± 1.9 | 0.743 |
 2 years vs. baseline | 28 | 4.6 ± 17.4 | 9.4 ± 22.9 | -0.8 ± 2.5 | 0.162 |
CTC follow-up (months) – median (IQR) | 74 | 13.1 (6.8, 24.1) | 17.9 (6.8, 23.9) | 12.7 (6.2, 24.3) | 0.837 |