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Fig. 2 | BMC Cancer

Fig. 2

From: Targeting the transcriptional activity of STAT3 by a novel fusion protein

Fig. 2

KRAB-STAT3 inhibits the endogenous STAT3 transcriptional activity. A–D, PCR of STAT3 and target genes in the control and monoclonal A375 cells represented as mean ± SD; n = 3; Student’s t-test. E–H, Western blot of STAT3 and target genes in monoclonal A375 cells represented as mean ± SD; n = 3; Student’s t test, original blots were in Supplementary Fig. 2. I-J, Immunofluorescence of c-Myc and STAT3 in monoclonal A375 cells, NS: no significance. Arrows show that the cytoplasm retained STAT3. Bars = 50 μm

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