Association between c-type lectin-like receptor 2 and microsatellite instability in colorectal cancer: a cross-sectional study

Table 4 Associations between clinical factors and microsatellite instability status

Variables	β	OR (95% CI)	p value
Age (years)	−0.040	0.961 (0.930–0.993)	0.019*
BMI (kg/m²)	0.147	1.159 (1.049–1.280)	0.004**
WBC (×10⁹/L)	0.141	1.151 (1.022–1.296)	0.020*
Hemoglobin (g/L)	−0.006	0.994 (0.981–1.007)	0.358
CLEC-2 (pg/mL) (≤ 166.3 vs > 166.3)	2.096	8.132 (4.047–16.341)	< 0.001***
Tumor size (cm) (≥ 5.0 vs < 5.0)	0.949	2.582 (1.332–5.006)	0.005**
Tumor location (Proximal vs Distal)	1.373	3.948 (1.968–7.920)	< 0.001***
Histological type (Mucinous vs Non-mucinous)	1.037	2.820 (1.286–6.187)	0.010*
Lymphatic invasion (Presence vs Absence)	−0.365	0.694 (0.267–1.806)	0.455
Lymph node metastasis (Presence vs Absence)	0.219	1.245 (0.133–11.663)	0.848
Stage (III + IV vs I + II)	−1.031	0.357 (0.039–3.228)	0.359

Values are logistic regression coefficient and odds ratio with 95% confidence interval. β, logistic regression coefficient; OR odds ratio, CI confidence interval; other abbreviation as in Table 1. *p < 0.05; **p < 0.01; ***p < 0.001 vs. the values of MSS group

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