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Table 2 Clinicopathological characteristics in the patients with or without sarcopenia

From: Use of computed tomography-derived body composition to determine the prognosis of patients with primary liver cancer treated with immune checkpoint inhibitors: a retrospective cohort study

 

Sarcopenia

(N = 68)

Non sarcopenia

(N = 104)

p value

Age, mean ± SD

51.8 ± 12.2

51.2 ± 11.3

0.729

Gender, N (%)

  

0.002

 Male

52(76.5)

97(93.3)

 

 Female

16(23.5)

7(6.7)

 

Body mass index (kg/m2), median (IQR)

20.5(18.3–24.2)

22.7(21.0–24.2)

0.002

Viral status, N (%)

  

0.036

 HCV

1(1.5)

2(1.9)

 

 HBV

56(82.3)

95(91.4)

 

 HCV + HBV

0(0.0)

2(1.9)

 

 None

11(16.2)

5(4.8)

 

Alcohol consumption, N (%)

  

0.452

  > 80 g per day

6(8.8)

13(12.5)

 

Smoking status, N (%)

  

0.261

 Never

45(66.2)

56(53.9)

 

 former

7(10.3)

12(11.5)

 

 current

16(23.5)

36(34.6)

 

BCLC stage, N (%)

  

0.392

 B

12(17.6)

24(23.1)

 

 C

56(82.4)

80(76.9)

 

ECOG-PS, N (%)

  

0.594

 0

33(48.5)

59(56.7)

 

 1

29(42.7)

39(37.5)

 

 2

4(5.9)

5(4.8)

 

 3

2(2.9)

1(1.0)

 

Child-Pugh Class, N (%)

  

0.266

 A

54(79.4)

84(80.8)

 

 B

12(17.7)

20(19.2)

 

 C

2(2.9)

0(0.0)

 

Comorbidity, N (%)

 Hypertension (yes/no)

17/51(25.0/75.0)

18/86(17.3/82.7)

0.221

 Diabetes (yes/no)

10/58(14.7/85.3)

10/94(9.6/90.4)

0.309

 Liver Cirrhosis (yes/no)

33/35(48.5/51.5)

69/35(66.3/33.7)

0.020

Previous treatment (yes/no), N (%)

60/8(88.2/11.8)

94/10(90.4/9.6)

0.653

Baseline metastasis (yes/no), N (%)

59/9(86.8/13.2)

76/28(73.1/26.9)

0.033

  1. SD Standard deviation, IQR Interquartile range, HCV Hepatitis s C virus, HBV Hepatitis B virus, BCLC Barcelona Clinic Liver Cancer, ECOG Eastern Cooperative Oncology Group, PS Performance status