Table 1 Baseline characteristics of patients with PLC treated with ICIs
Characteristic | All patients (N = 172) |
|---|---|
Age, mean ± SD | 51.4 ± 11.7 |
Gender male, N (%) | 149(86.6) |
Body mass index (kg/m2), median (IQR) | 22.2(20.0–24.2) |
  < 18.5 (underweight), N (%) | 22(12.8) |
 18.5 ~ 24.9 (normal weight), N (%) | 113(65.7) |
  ≥ 25 (overweight), N (%) | 37(21.5) |
Viral status, N (%) | |
 HCV/HBV/HCV + HBV/none | 3/153/2/14(1.7/89.0/1.2/8.1) |
Alcohol consumption, N (%) | |
  > 80 g per day | 19(11.0) |
Smoking status, N (%) | |
 Never/former/current | 101/19/52(58.7/11.0/30.2) |
BCLC stage, N (%) | |
 B/C | 36/136(20.9/79.1) |
ECOG-PS, N (%) | |
 0/1/2/3 | 92/68/9/3(53.5/39.5/5.2/1.8) |
Child-Pugh Class, N (%) | |
 A/B/C | 138/32/2(80.2/18.6/1.2) |
Comorbidity, N (%) | |
 Hypertension (yes/no) | 35/137(20.3/79.7) |
 Diabetes (yes/no) | 20/152(12.2/87.8) |
 Liver Cirrhosis (yes/no) | 102/70(59.3/40.7) |
Previous treatment (yes/no), N (%) | 154/18(89.5/10.5) |
Baseline metastasis (yes/no), N (%) | 135/37(78.5/21.5) |
Body composition variable | |
 SMI (cm2/m2), median (IQR) | 46.0(41.1–52.5) |
 SMD (HU), median (IQR) | 39.9(36.4–44.0) |
 VATI (cm2/m2), median (IQR) | 29.0(15.1–46.6) |
 SATI (cm2/m2), median (IQR) | 33.7(19.0–51.4) |
 TATI (cm2/m2), median (IQR) | 66.9(35.2–99.6) |
 VSR, median (IQR) | 0.84(0.59–1.19) |