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Fig. 3 | BMC Cancer

Fig. 3

From: Integration of metabolites from meta-analysis with transcriptome reveals enhanced SPHK1 in PDAC with a background of pancreatitis

Fig. 3

Metabolic networks, genes and integration of transcriptome (A) Metabolites mapped from selected studies (red) and their networks of significance operating in chronic pancreatitis and pancreatic cancer patients. PIGC, PPIB and PKM are upregulated in CP, PDAC-CP. AZGP1, EGLN1 and GNMT are downregulated in CP and PDAC-CP. SPHK1 upregulated in PDAC-CP and AK1RB1, KMT2C are downregulated in PDAC-CP. These genes are mapped to their respective metabolic pathways (B) Integration of metabolome and transcriptome yielding 102 common genes in chronic pancreatitis and pancreatic cancer human tissues (C) Distribution of genes and types of metabolites

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BMC Cancer

ISSN: 1471-2407

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