Fig. 4.

Fifty-Eight year-old woman with ER + /HER2- locally advanced breast cancer on the right side treated with NET protocol, mastectomy and ALND. A and B Axial T2-weighted and T1-weighted MR images, respectively. From left to right: baseline T2-weighted (A) and T1-weighted (B) show a metastatic LN with irregular edge, displaced hilum, signal inhomogeneity, perinodal infiltration and maximal diameter of 28.6 mm; images obtained during and after NET, T2-weighted (A) and T1-weighted (B), shows that the node continues to have irregular edge, displaced hilum, that signal inhomogeneity and perinodal infiltration persist, and maximal diameter of 23.7 mm and 15.3 mm, respectively, these findings indicate malignancy. C Corresponding photomicrograph (H and E, original magnification × 200) shows widespread tumor deposition in LN with irregular border at baseline