Table 2 Multivariate relationship between study parameters and PD1 and PDL1 positivity in tumoral and background cells
From: Expression of PD1 and PDL1 as immune-checkpoint inhibitors in mantle cell lymphoma
Variable | p | Exp(B) | 95% C.I.for EXP(B) | ||
|---|---|---|---|---|---|
Lower | Upper | ||||
Gender | PD1 positivity in tumor cell | 0.999 | < 0.001 | < 0.001 | - |
PDL1 positivity in tumor cells | 0.999 | < 0.001 | < 0.001 | - | |
PD1 positivity in background cells | 0.999 | < 0.001 | < 0.001 | - | |
PDL1 positivity in background cells | 0.505 | 0.028 | < 0.001 | 1045.587 | |
Age | PD1 positivity in tumor cell | 0.503 | 0.953 | 0.829 | 1.096 |
PDL1 positivity in tumor cells | 0.389 | 1.050 | 0.939 | 1.174 | |
PD1 positivity in background cells | 0.996 | 0.011 | < 0.001 | - | |
PDL1 positivity in background cells | 0.605 | 0.885 | 0.556 | 1.408 | |
Size | PD1 positivity in tumor cell | 0.389 | 0.421 | 0.059 | 3.017 |
PDL1 positivity in tumor cells | 0.658 | 0.514 | 0.027 | 9.830 | |
PD1 positivity in background cells | 0.966 | 1.873E + 41 | < 0.001 | - | |
PDL1 positivity in background cells | 0.467 | < 0.001 | < 0.001 | 3.481E + 15 | |
Aggressive tumor | PD1 positivity in tumor cell | 0.999 | < 0.001 | < 0.001 | - |
PDL1 positivity in tumor cells | 0.999 | 289,378,866.6 | < 0.001 | - | |
PD1 positivity in background cells | 0.999 | 633,488,326.857 | < 0.001 | - | |
PDL1 positivity in background cells | 0.488 | 379.467 | < 0.001 | 7,470,964,009 | |