Fig. 6

Correlation between gene signature and immunophenotyping, immune cell and somatic mutation. A. The multiple box diagram shows the expression differences of four characteristic genes between the immunity_L and immunity_H groups. B. Heat maps show the correlation between the four characteristic genes that build the gene signature and the immune cells. Blue indicates a negative correlation; red indicates a positive correlation. C. Tumor mutation load (TMB) between the two different immune gene subtypes. D. The Kaplan–Meier curve was used to analyze the survival outcomes of the BLCA patients between the high and low TMB groups. E. The Kaplan–Meier curve was used to analyze the risk scores and survival of patients in the TMB group. In both the high and low TMB groups, the patients with BLCA in the low-risk group have survival advantages