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Table 6 Diagnostic indicators of imaging modalities

From: Randomized trial of surveillance with abbreviated MRI in women with a personal history of breast cancer– impact on patient anxiety and cancer detection

  Mammography A-MRIa P value**
False negative 6 0  
True negative 183 78  
False positive 8 21  
True positive 1 5  
Recall rate 9/198 (4.5%) 25/104 (25%)  < 0.00001
Biopsy rate 6/198 (3.0%) 19/104 (18.3%)  < 0.00001
CDR 1/198 (0.5%) 5/104 (4.8%) 0.0109
PPV2 (recommended) 1/6 (16.7%) 5/20 (25%) 0.59
PPV3 (performed) 1/6 (16.7%) 5/19 (26.3%) 0.557
Sensitivity (%, CI) 1/7 (14.2%, 0.36–57.8) 5/5 (100%) 0.004
Specificity (%, CI) 183/191 (95.8%, 91.9–98) 78/99 (78.8%) 0.00001
  1. CI 95% confidence intervals, A-MRI Abbreviated breast MRI, CDR Cancer detection rate (per 1000 women), PPV2 Positive predictive value for biopsies recommended, PPV3 Positive predictive value for biopsies performed, CI Confidence interval
  2. aincluding intra-mammary findings only,
  3. **excluding extra-mammary findings, chi-square test for comparison between groups