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Table 3 Univariate analysis for overall and disease-free survival

From: Metabolic activity determines survival depending on the level of lymph node involvement in cervical cancer

 

Overall Survival

Disease-Free Survival

HR (95%CI)

p-value

HR (95%CI)

p-value

Age ≥ 55 vs < 55 years (ref.)

0.58 (0.28–1.17)

0.124

0.62 (0.35–1.12)

0.109

Histological subtype other than squamous vs squamous (ref.)

0.99 (0.35–2.78)

0.988

0.82 (0.33–2.05)

0.668

FIGO stage IIB-IVA vs IB2-IIA2 (ref.)

3.54 (1.26–9.94)

0.010

3.38 (1.45–7.88)

0.003

Tumor size on imaging (cm)

1.35 (1.11–1.64)

0.003

1.27 (1.08–1.50)

0.004

Tumor SUVmax

1.07 (1.03–1.12)

0.001

1.05 (1.01–1.09)

0.012

Tumor MTV (/10 cc)

1.10 (1.04–1.16)

 < 0.001

1.07 (1.03–1.13)

0.002

PLN SUVmax

1.15 (1.05–1.26)

0.002

1.12 (1.03–1.21)

0.008

Number of PLN with uptake at FDG-PET/CT

1.19 (1.07–1.33)

0.002

1.17 (1.05–1.30)

0.004

  1. HR Hazard Ratio, CI Confidence Interval, FIGO International Federation of Gynecology and Obstetrics, SUVmax maximum standardized uptake value, MTV metabolic tumor volume, PLN pelvic lymph node, FDG-PET/CT fluorodeoxyglucose-positron emission tomography/computed tomography