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Fig. 2 | BMC Cancer

Fig. 2

From: Polygenic risk scores indicate extreme ages at onset of breast cancer in female BRCA1/2 pathogenic variant carriers

Fig. 2

Boxplots and two-sided Welch’s t-test p values of standardized polygenic risk scores (overall breast cancer (BC), estrogen receptor (ER)-positive BC (ER+), ER-negative BC (ER-) PRS) of 183 BRCA1 and 112 BRCA2 pathogenic variant carriers, who were either diagnosed with BC before the age of 35 years (early diagnosis, ED) or were unaffected at least until the age of 60 years (late/no diagnosis, LD)

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