Table 1 Baseline characteristics of patients with HCC

N

214

109

Age (years)

52.6 ± 9.2

52.7 ± 10.1

0.966

BMI (kg/m²)

24.2 ± 3.8

22.0 ± 2.6

 < 0.001

Sex (male, %)

162 (75.7)

82 (75.2)

0.926

HBsAg (%)

190 (88.8)

65 (59.6)

 < 0.001

Hepatitis C (%)

11 (5.1)

2 (1.8)

0.153

Cirrhosis (%)

196 (91.6)

41 (37.6)

 < 0.001

Child Pugh score

 < 0.001

  A

205 (95.8)

85 (78.0)

  B

9 (4.2)

24 (22.0)

Vascular invasion

0.631

  No

186 (86.9)

24 (22.0)

  Yes

28 (13.1)

85 (78.0)

Tumor number

0.631

  Single

183 (85.5)

91 (83.5)

  Multiple

31 (14.5)

18 (16.5)

Tumor differentiation

 < 0.001

  Poor

38 (17.8)

50 (45.9)

  Moderate/well

176 (82.2)

59 (54.1)

Capsule

0.001

  Complete

183 (85.5)

77 (70.6)

  Incomplete

31 (14.5)

32 (29.4)

Tumor size (cm)

4.9 ± 2.9

6.3 ± 4.2

0.002

MELD score

-1.84 (-3.58 to 0.02)

1.57 (-4.20 to 0.90)

0.451

FIB-4

1.9 (1.4–3.2)

1.9 (1.1–3.2)

0.417

APRI

0.6 (0.4–0.9)

0.7 (0.4–1.2)

0.439

PALBI

-3.3 (-3.6 to -3.1)

-4.8 (-5.2 to -4.2)

 < 0.001

ALBI

-2.6 (-2.9 to -2.3)

-2.0 (-2.4 to -1.7)

 < 0.001

AFP (ng/mL)

14.8 (4.1–227.5)

23.7 (4.7–471.2)

0.390

WBC (× 10⁹/L)

5.84 ± 2.10

8.39 ± 3.98

 < 0.001

Haemoglobin (g/L)

142.0 ± 17.3

122.2 ± 23.7

 < 0.001

Platelet count (× 10⁹/L)

161.5 ± 63.2

177.9 ± 90.6

0.093

MPV (fL)

10.6 ± 1.4

11.1 ± 1.1

 < 0.001

PDW (%)

15.2 ± 2.4

13.2 ± 2.2

 < 0.001

INR

1.06 ± 0.09

1.21 ± 0.26

 < 0.001

Albumin (g/L)

39.5 ± 4.6

34.3 ± 5.8

 < 0.001

Creatinine (μmol/L)

76.8 ± 15.0

60.6 ± 15.5

 < 0.001

AST (U/L)

35 (28–47)

51 (31–88)

 < 0.001

ALT (U/L)

39 (28–52)

39 (26–60)

0.589

γ-GGT (U/L)

49 (32–84)

78 (44–135)

 < 0.001

Total bilirubin (μmol/L)

13.9 (10.4–18.7)

18.2 (14.1–25.6)

 < 0.001