Table 1 Patient characteristics overall and according to muscle density
From: Effect of musculature on mortality, a retrospective cohort study
Characteristic | All n = 403 | Myosteatosis n = 150 (37.2) | Normal Musculature n = 253 (62.8) | p |
|---|---|---|---|---|
Age (years) | 60.9 (10.3) | 65.2 (10.9) | 58.4 (9.0) | < 0.0001 |
Sex | < 0.0001 | |||
Male | 329 (81.6) | 97 (64.7) | 232 (91.7) | |
Female | 74 (18.4) | 53 (35.3) | 21 (8.3) | |
Race | 0.14 | |||
White | 361 (89.6) | 130 (86.7) | 231 (91.3) | |
BIPOC | 42 (10.4) | 20 (13.3) | 22 (8.7) | |
BMI (kg/m2) | 27.8 (5.8) | 25.3 (6.1) | 29.3 (5.1) | < 0.0001 |
SMI (cm2/m2) | 53.1 (11.7) | 44.3 (8.4) | 58.3 (10.1) | < 0.0001 |
VAT (cm2) | 163.3 (96.3) | 129.6 (88.1) | 183.3 (95.5) | < 0.0001 |
SAT (cm2) | 181.4 (94.7) | 165.7 (102.9) | 190.7 (88.5) | 0.01 |
IMAT (cm2) | 13.0 (8.1) | 16.4 (9.3) | 11.0 (6.5) | < 0.0001 |
TAT (cm2) | 357.7 (164.5) | 311.8 (168.0) | 385.0 (156.4) | < 0.0001 |
SMD (HU) | 38.6 (8.3) | 30.5 (5.8) | 43.4 (5.3) | < 0.0001 |
Low Muscle Mass | < 0.0001 | |||
Yes | 135 (33.5) | 85 (56.7) | 50 (19.8) | |
No | 268 (66.5) | 65 (43.3) | 203 (80.2) | |
Comorbidities | 2.2 (1.8) | 2.3 (1.8) | 2.1 (1.9) | 0.33 |
Tumor site | 0.001 | |||
Oropharynx | 206 (51.1) | 61 (40.7) | 145 (57.3) | |
Larynx | 100 (24.8) | 51 (34.0) | 49 (19.4) | |
Other | 32 (7.9 | 38 (25.3) | 59 (23.3) | |
AJCC stage | 0.005 | |||
0-II | 137 (34.0) | 39 (26.0) | 98 (38.7) | |
III | 100 (24.8) | 40 (26.7) | 60 (23.7) | |
IV | 166 (41.2)_ | 71 (47.3) | 95 (37.6) | |
HPV | < 0.0001 | |||
Positive | 164 (40.7) | 40 (26.7) | 124 (49.0) | |
Negative | 96 (23.8) | 48 (32.0) | 48 (19.0) | |
Inapplicable | 143 (35.5) | 62 (41.3) | 81 (32.0) | |
Treatment | 0.001 | |||
RT only | 27 (6.7) | 18 (12.0) | 9 (3.6) | |
RT + Chemotherapy | 376 (93.3) | 132 (88.0) | 244 (96.4) | |
Smoking status | 0.02 | |||
Current | 110 (27.3) | 50 (33.3) | 60 (23.7) | |
Former | 202 (50.1) | 76 (50.7) | 126 (49.8) | |
Never | 91 (22.6) | 24 (16.0) | 67 (26.5) | |
Alcohol consumption | 0.41 | |||
Current | 228 (56.6) | 81 (54.0) | 147 (58.1) | |
Former | 88 (21.8) | 37 (24.7) | 51 (20.2) | |
Never | 69 (17.1) | 23 (15.3) | 46 (18.2) | |
Unknown | 18 (4.5) | 9 (6.0) | 9 (3.6) | |
Unplanned hospitalizations | 0.12 | |||
None | 308 (76.4) | 121 (80.7) | 187 (73.9) | |
One | 95 (23.6) | 29 (19.3) | 66 (26.1) |