Fig. 6

Stromal cell-derived CXCL1 enhances oncogenic potential of HeLa cells via a paracrine manner. A CXCL1 protein level in PHM1-41 cells overexpressing CXCL1 and their mock controls-derived supernatant was determined using ELISA assay. B The growth ability of HeLa cells treatment with CM from PHM1-41 cells overexpressing CXCL1 and their mock controls was detected by CCK-8 assay. C-D The effect of various proportions of CM derived from PHM1-41 cells overexpressing CXCL1 and their mock controls on the HeLa cell migration was explored by transwell analysis. *P < 0.05, **P < 0.01