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Fig. 4 | BMC Cancer

Fig. 4

From: Comprehensive bioinformatic analysis reveals a cancer-associated fibroblast gene signature as a poor prognostic factor and potential therapeutic target in gastric cancer

Fig. 4

Correlation of the six key CAF markers with the CAF infiltration and other CAF markers. The correlation of A COL1A1, B COL1A2, C COL3A1, D COL5A1, E FN1, F SPARC with CAF infiltration in gastric cancer (TIDE algorithm in TIMER2.0. was used to infer the CAF infiltration levels in TCGA stomach adenocarcinoma samples). G Correlation heatmap for the six key CAF markers in gastric cancer (GC) with an extended list of other CAF markers. Correlation data was extracted from TIMER2.0 using the “gene correlation” module. Heatmap was created in imageGP using hierarchical clustering. The six key CAF markers in GC are shown with black arrows. Genes are classified as CAF-specific markers (red), CAF markers (blue), and GC-CAF markers (CAF markers identified in GC) (lilac)

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BMC Cancer

ISSN: 1471-2407

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