From: A predictive model for advanced oropharyngeal cancer patients treated with chemoradiation
 | Univariate | Multivariate | ||||||
---|---|---|---|---|---|---|---|---|
OR | 95% CI | p-value | OR | 95% CI | p-value | |||
Gender | ||||||||
 Female | Ref. |  |  |  | Ref. |  |  |  |
 Male | 3.031 | 0.362 | 25.412 | 0.307 | 2.386 | 0.249 | 22.817 | 0.450 |
Age | ||||||||
  < 60y | Ref. |  |  |  | Ref. |  |  |  |
  ≥ 60y | 1.698 | 0.830 | 3.473 | 0.147 | 2.200 | 0.881 | 5.495 | 0.091 |
T | ||||||||
 T1 + 2 | Ref. |  |  |  |  |  |  |  |
 T3 + 4 | 3.625 | 1.476 | 8.906 | 0.005* |  |  |  |  |
N | ||||||||
 N0 + 1 | Ref. |  |  |  | Ref. |  |  |  |
 N2 | 1.202 | 0.500 | 2.892 | 0.681 | 1.050 | 0.292 | 3.774 | 0.940 |
 N3 | 3.625 | 1.080 | 12.167 | 0.037* | 1.552 | 0.267 | 9.023 | 0.624 |
Stage | ||||||||
 III | Ref. |  |  |  | Ref. |  |  |  |
 IVa | 0.925 | 0.275 | 3.109 | 0.900 | 0.575 | 0.104 | 3.172 | 0.525 |
 IVb | 6.250 | 1.678 | 23.275 | 0.006* | 2.700 | 0.391 | 18.629 | 0.314 |
Subsite | ||||||||
 Tonsil | Ref. |  |  |  |  |  |  |  |
 Soft palate | 0.552 | 0.113 | 2.695 | 0.463 |  |  |  |  |
 Tongue base | 0.753 | 0.194 | 2.921 | 0.681 |  |  |  |  |
 Pharyngeal wall | 2.563 | 1.060 | 6.196 | 0.037* |  |  |  |  |
Side | ||||||||
 R | Ref. |  |  |  |  |  |  |  |
 L | 1.019 | 0.496 | 2.092 | 0.960 |  |  |  |  |
Previous treated cancer | ||||||||
 None | Ref. |  |  |  |  |  |  |  |
 Yes | 0.705 | 0.184 | 2.698 | 0.610 |  |  |  |  |
Syn−/Meta-chornous cancer | ||||||||
 None | Ref. |  |  |  |  |  |  |  |
 Yes | 1.250 | 0.466 | 3.351 | 0.657 |  |  |  |  |
Differentiation | ||||||||
 Well | Ref. |  |  |  |  |  |  |  |
 Moderately + Poorly | 0.705 | 0.345 | 1.441 | 0.338 |  |  |  |  |
HPV (p16) | ||||||||
 Positive | Ref. |  |  |  |  |  |  |  |
 Negative | 1.455 | 0.447 | 4.733 | 0.534 |  |  |  |  |
Smoking habit | ||||||||
 No | Ref. |  |  |  |  |  |  |  |
 Yes, quitted | 1.022 | 0.374 | 2.798 | 0.966 |  |  |  |  |
 Yes, persistence | 0.894 | 0.365 | 2.194 | 0.808 |  |  |  |  |
BMI | ||||||||
  < 22 | Ref. |  |  |  |  |  |  |  |
  ≥ 22 | 0.365 | 0.176 | 0.758 | 0.007* |  |  |  |  |
Hemoglobulin (gm/dl) | ||||||||
  ≥ 13.5 | Ref. |  |  |  | Ref. |  |  |  |
  < 13.5 | 6.206 | 2.622 | 14.689 | 0.000* | 5.846 | 2.169 | 15.754 | 0.000* |
Lymphocyte count (103/μl) | ||||||||
  ≥ 1.85 | Ref. |  |  |  |  |  |  |  |
  < 1.85 | 1.690 | 0.792 | 3.606 | 0.175 |  |  |  |  |
Monocyte count (102/μl) | ||||||||
  < 0.56 | Ref. |  |  |  |  |  |  |  |
  ≥ 0.56 | 1.354 | 0.663 | 2.765 | 0.405 |  |  |  |  |
Platelet count (103/μl) | ||||||||
  < 239 | Ref. |  |  |  |  |  |  |  |
  ≥ 239 | 5.152 | 2.243 | 11.830 | 0.000* |  |  |  |  |
Neutrophil count (103/μl) | ||||||||
  < 7.5 | Ref. |  |  |  |  |  |  |  |
  ≥ 7.5 | 3.124 | 1.411 | 6.917 | 0.005* |  |  |  |  |
LMR | ||||||||
  < 1.9 | Ref. |  |  |  |  |  |  |  |
  ≥ 1.9 | 0.692 | 0.313 | 1.533 | 0.364 |  |  |  |  |
PLR | ||||||||
  < 157 | Ref. |  |  |  |  |  |  |  |
  ≥ 157 | 2.100 | 1.004 | 4.373 | 0.049* |  |  |  |  |
NLR | ||||||||
  < 5.1 | Ref. |  |  |  |  |  |  |  |
  ≥ 5.1 | 2.149 | 1.024 | 4.511 | 0.043* |  |  |  |  |
SIRI | ||||||||
  < 553.7 | Ref. |  |  |  |  |  |  |  |
  ≥ 553.7 | 4.199 | 1.479 | 11.922 | 0.007* |  |  |  |  |
SII | ||||||||
  <  1820 | Ref. |  |  |  | Ref. |  |  |  |
  ≥ 1820 | 8.212 | 3.066 | 21.995 | 0.000* | 4.777 | 1.440 | 15.846 | 0.011* |