Univariable analysis | ||||
Outcome (number of studies reporting outcome) | Factor | Times identified as prognostic | Total times tested | Studies which identified factor as prognostic |
Overall survival (n = 17) | Lower HPV16 load | 2 | 3 | |
Neutrophilia | 2 | 2 | ||
Anaemia | 2 | 2 | ||
Locoregional failure (n = 11) | Lower HPV16 load | 2 | 3 | |
Disease-free survival (n = 11) | Leukocytosis | 2 | 2 | |
Neutrophilia | 2 | 2 | ||
Multivariable analysis | ||||
Outcome (number of studies reporting outcome) | Factor | Times identified as prognostic | Factor effect range (HR) | Studies which identified factor as prognostic |
Overall survival (n = 17) | Leukocytosis | 2 | 4.60 – 19.90 | |
Neutrophilia | 2 | 4.40 – 22.70 | ||
Locoregional failure (n = 11) | Lower HPV16 load | 2 | 3.57 – 4.51 | |
Disease-free survival (n = 11) | Leukocytosis | 2 | 6.90 – 7.10 | |
Neutrophilia | 2 | 5.00 – 7.60 | ||
Anaemia | 2 | 2.50 – 5.30 |