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Fig. 4 | BMC Cancer

Fig. 4

From: MIF/CXCR4 signaling axis contributes to survival, invasion, and drug resistance of metastatic neuroblastoma cells in the bone marrow microenvironment

Fig. 4

In vivo effects of BM in a LAN-1 xenograft model: A) Engraftment curves for each group, reported at 100 mm3 tumor size. B) Tumor survival curves for each group, reported at 1500 mm3 tumor size. C) Histology of primary subcutaneous LAN-1 tumors by H&E, hNu, and Ki-67 staining (40x). D) Ki-67 quantification of stained FFPE sections (n = 6) was quantified using ImageJ software. Mann-Whitney test. (*) P < 0.05

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