Comparing the efficacy and safety of cisplatin and other platinum-based chemotherapies in locally advanced nasopharyngeal carcinoma: a systematic review and meta-analysis

Table 1 Characteristics of the eligible studies

Study	Inclusion period	Register	Type of study	Phase	chemoradiotherapy	No.Patients	No.male	Mean Age (Exp/con)	AJCC Stage	Median follow-up(year)
Lv et al	2013–2015	ChiCTR-TRC-13003285	RCT	III	IC + CCRT	502	362	43.5/44	III–IVB	75.3
Tang et al	2011–2012	NCT 01479504	RCT	III	IC + CCRT	223	NR	45.1/45.3	III–IV	35.1
Linquan et al	2012–2014	NCT01540136	RCT	III	CCRT	402	302	44/45	II–IVB	47
Hu et al	2014–2015	NR	RCT	III	IC	62	45	50.2/49.8	III–IV	NR
Liu et al	2009–2011	NR	RE	FE	IC + CCRT	186	119	NR	II–IVB	68
Zhan et al	2012–2017	NR	RE	FE	IC + CCRT	226	184	NR	III–IVA	39.5
Cao et al	2009–2010	NR	RCT	III	IC	100	NR	NR	III–IVA	NR
Imjai et al	1999–2004	NR	RCT	III	CCRT + AC	206	126	50/46	III–IVB	26.3

RCT randomized controlled trials, IC Induction chemotherapy, CCRT Concurrent chemoradiotherapy, AC Adjuvant chemotherapy, Con control group (cisplatin-based group), Exp experimental group (other platinum-based group), NA not available, Re retrospetive study, NR not reported, FE fail to extract

ISSN: 1471-2407