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Fig. 6 | BMC Cancer

Fig. 6

From: Aberrant expression of GSTM5 in lung adenocarcinoma is associated with DNA hypermethylation and poor prognosis

Fig. 6

5-Aza-CdR demethylated the GSTM5 promoter region and promoted GSTM5 expression in LUAD cells. A The CpG island of GSTM5 was predicted by MethPrimer. B Methylation status of the promoter region of GSTM5 in lung cancer cells. C Effect of 5-Aza-CdR on GSTM5 demethylation in LUAD cells. D GSTM5 mRNA expression analysis by RT-PCR in LUAD cells following 5-Aza-CdR treatment for 48 h. Full length gels and blots are also included in additional file 4. M: amplification product of methylated primers; U: amplification product with non-methylated primers. *P < 0.05

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BMC Cancer

ISSN: 1471-2407

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