Associations of different immune checkpoints-expressing CD4+ Treg/ T cell subsets with disease-free survival in colorectal cancer patients

Table 2 Summary of the significant associations of high frequencies of different CD4⁺ T cell subsets with DFS

CD4⁺ T cell subsets	PBMCs	TILs	NILs
FoxP3⁺	Unfavorable	Favorable	None
Helios⁺	Unfavorable	None	None
FoxP3⁺Helios⁺	Unfavorable	None	None
FoxP3⁻Helios⁻	None	Unfavorable	None
FoxP3⁺Helios⁻PD-1⁺	Unfavorable	None	None
FoxP3⁺Helios⁺CTLA-4⁺	Unfavorable	None	None
FoxP3⁺Helios⁻CTLA-4⁺	Unfavorable	None	None
FoxP3⁻Helios⁺CTLA-4⁺	Unfavorable	None	None
TIM-3⁺	Favorable	None	None
FoxP3⁺Helios⁺TIM-3⁺	Favorable	None	None
FoxP3⁻Helios⁺TIM-3⁺	Favorable	None	None

ISSN: 1471-2407