Fig. 5From: Associations of different immune checkpoints-expressing CD4+ Treg/ T cell subsets with disease-free survival in colorectal cancer patientsKaplan–Meier curves of DFS based on frequencies of CD4+FoxP3+Helios− expressing immune checkpoints in PBMCs, TILs, and NILs. Patients with high frequencies of PD-1+ (A), CTLA-4+ (B), and TIM-3+ (C), in CD3+CD4+FoxP3+Helios− T cells, were compared with those with low frequencies of these subsetsBack to article page