Fig. 1

Kaplan–Meier curves of DFS based on frequencies of CD25⁺, FoxP3⁺, and Helios⁺ in PBMCs, TILs, and NILs. Patients with high frequencies of CD25⁺ (A), FoxP3⁺ (B), and Helios⁺ (C), in CD3⁺CD4⁺ T cells, were compared with those with low frequencies of these subsets. Patient numbers investigated are indicated on the survival curves for each cell population in all figures