Fig. 7
From: MUC3A promotes the progression of colorectal cancer through the PI3K/Akt/mTOR pathway
Knockout of MUC3A repressed cell growth in vivo. A-C The growth curve of CRC cells in vivo. A Without any treatment. B With rapamycin treatment (4 mg/kg, per day). C With 5-FU treatment (20 mg/kg, per 2 days). D Apoptosis rate of xenografts detected by TUNEL staining. E Expression of Ki67, p53, p21 and PI3K/Akt/mTOR pathway-associated proteins detected by IHC (**P < 0.01, ***P < 0.001)