Table 2 Results of univariate and multivariate analysis

Variable

 Age

1,02 (1,02–1,03)

 < 0,0001

1,01 (1,01–1,02)

 < 0,0001

Gender

 Female

883

74

60

Reference

Reference

 Male

1203

63

50

1,33 (1,12–1,58)

0,0005

1,19 (1,00–1,41)

0,04

 Melanoma body site

0,58

 Breslow

1,08 (1,06–1,10)

 < 0,0001

1,06(1,04–1,08)

 < 0,0001

Ulceration

 Not

1126

76

63

Reference

Reference

 Yes

960

60

42

1,86 (1,57–2,20)

 < 0,0001

1,30 (1,08–1,56)

0,004

 Number of positive SN

1,22 (1,06–1,41)

0,0066

0,16

SN tumor burden

 0,01–0,4 mm

577

82

68

Reference

 0,42–0,96 mm

471

76

58

1,27(1,01–1,59)

 0,97–3 mm

586

66

52

1,89 (1,54–2,34)

 3,1–35 mm

452

49

34

3,51 (2,74–4,49)

 < 0,0001

1,04 (1,03–1,06)

 < 0,0001

NSN Status

 Negative

1633

75

61

Reference

 Positive

453

46

31

 < 0,0001

2,06(1,72–2,5)

 < 0,0001