Fig. 3From: Is it sufficient to evaluate metastatic bone involvement in breast cancer using SPECT/CT? A new approach of SPECT/CT-guided targeted bone marrow biopsySPECT/CT-guided targeted bone marrow biopsy in the manubrium. Anterior bone scintigraphy, SPECT/CT fusion tomography image, biopsy image, and biopsy pathology image of a patient with invasive ductal carcinoma of the right breast 2Ā years after surgery (female, 30-year-old). AĀ The anterior bone scintigraphy suggested abnormally increased bone metabolism on the right side of the manubrium (black arrow). B, CĀ SPECT/CT fusion tomography results showed bone destruction in the location of increased metabolism on the right side of the sternal body. DĀ SPECT/CT-guided percutaneous biopsy of the biological target in the sternal body. EĀ Pathology and immunohistochemistry results suggested myofibroblastoma. Light microscopy results revealed a small amount of bone and dead bone tissues, polygonal cells between bone trabeculae, and nucleoli (HEāĆā100)Back to article page