Fig. 1

SPECT/CT-guided targeted bone marrow biopsy in the sternal body. Anterior bone scintigraphy, SPECT/CT fusion tomography image, biopsy image, and biopsy pathology image of a patient with invasive ductal carcinoma of the left breast (female, 44 years old). A The anterior bone scintigraphy suggested increased focal abnormal metabolism in the sternal body (black arrow). B, C SPECT/CT fusion tomography showed bone destruction in a location of increased metabolism in the sternal body. D SPECT/CT-guided percutaneous biopsy of the biological target in the sternal body. E Pathological examination results suggested metastatic breast invasive ductal carcinoma, and light microscopy results revealed the nested distribution of tumour cells in the space between bones and dead bones, with obvious cell atypia combined with nuclear hyperchromic malformation (HE × 100)