Fig. 3
From: YAP1 is essential for malignant mesothelioma tumor maintenance
In vivo pharmacodynamic analysis of MSTO-211H-TEAD2-DN xenografts: A In this pharmacodynamic study, tumors were allowed to grow up to 300 mm.3 under glucose supplementation and were sampled just before doxycycline supplementation (time point 0, n = 5), 24 h (n = 5), 96 h (n = 5) and 216 h (n = 4) post doxycycline supplementation (time point 1, 2 & 3). B Western blot analysis of TEAD2-DN protein expression. Beta tubulin is used as a loading control. C mRNA expression by RT-qPCR. D TEAD-dependent transcription (deR)